Retatrutide

What Is Retatrutide?

Retatrutide is an investigational “triple-agonist” peptide, often called a “Triple-G”, because it targets:

• GLP-1
• GIP
• Glucagon

This combination affects appetite, metabolism, and fat utilization.

How Retatrutide Works

GLP-1

• Reduces appetite
• Slows gastric emptying
• Enhances insulin release after meals

GIP

• Improves insulin secretion
• Supports fat metabolism
• Helps regulate appetite

Glucagon

• Increases metabolic rate
• Promotes fat burning
• Boosts energy expenditure

The GLP-1 and GIP effects help counterbalance glucagon’s blood sugar effects.

Combined Metabolic Effects

• Reduced caloric intake
• Increased fat burning
• Improved insulin sensitivity
• Enhanced metabolic flexibility

Potential Benefits

• Significant weight loss
• Improved metabolic health
• Increased energy expenditure
• Advanced appetite control